The St. Dumitru Church built by Vasile Lupu is located in this town. Orhei is approximately 50 kilometers north of the capital, Chişinău. Orhei gets its name from Orhei Vechi, an active monastery near the village of Ivancea.
The name "Orhei" is, according to one theory, derived from the Hungarian word Őrhely, meaning "fortress", dating from the 13th century, when Hungarian forces built a series of defences in the area.
Orhei was home to many Jews prior to WWII, and has a large Jewish cemetery There is only one active synagogue left in the community. The main churches are Russian Orthodox. Also in the area are Baptist, a Seventh-day Adventist Church, The Church of Jesus Christ of Latter-day Saints, The Salvation Army and Jehovah's Witnesses.